Head of the Genomics and Epigenetics Division at the Garvan Institute of Medical Research in Sydney, Professor Clark is highly acclaimed internationally for her work in human epigenetics, and is best known for her pivotal contribution to the advancement of new sequencing technologies for DNA methylation and histone modification to investigate complex relationships between epigenetic alterations and gene control in normal and cancer cells.
Professor Clark’s research has initiated profound questions about the importance of epigenetics in early development and disease, especially in cancer. Within the last five years, she has demonstrated that epigenetic changes in cancer are not restricted to individual genes but can encompass genome-wide domains, resulting in widespread gene silencing and activation.
As well as leading the formation of the AEpiA, Professor Clark was also a founding member of the International Human Epigenome Consortium (IHEC).
“The Australian Academy of Science is the most highly regarded scientific body in Australia,” said Professor Clark. “I am extremely honoured and humbled to be elected as a Fellow.”