Dr Heather Lee
Dr Heather Lee completed her PhD at the Garvan Institute of Medical Research, where she investigated hormonal control of mammary gland development and breast cancer. Her research focused on the transcription factor, Elf5, which plays key roles in breast development during pregnancy and acquisition of anti-oestrogen resistance in breast cancer.
After discovering lineage-specific DNA methylation of the Elf5 promoter in the mammary epithelium, Heather decided to undertake post-doctoral research in the field of epigenetics.
In 2012, Heather relocated to Cambridge, UK, where she joined the laboratory of Professor Wolf Reik. Using mouse embryonic stem cells as an experimental model, she revealed unprecedented dynamic heterogeneity in DNA methylation. Heather also developed ground-breaking single-cell sequencing technologies for the parallel analysis of genome-wide DNA methylation and gene expression in the same single cell.
Heather joined the University of Newcastle in February 2017, where she leads a research group at the Hunter Medical Research Institute. Her current research focuses on epigenetic heterogeneity in acute myeloid leukaemia.
Early in 2008, Sue Clark brought a handful of epigenetics researchers from Australia together to form the Australian Epigenetics Alliance. The AEpiA has now grown to a membership of over 400, with members spanning not only Australasia, but the globe. We hosted our seventh flagship conference, Epigenetics 2017 in Brisbane, and our VIC team is busy preparing for Epigenetics 2020 in Melbourne in November – watch this space!